• Introduction
  • Why Almac?
  • People
  • Facilities
• Biomarker Discovery and Validation
  • Companion Diagnostics
  • Pharmacodynamic Biomarkers
  • Prognostic tests
  • Drug Repositioning
  • Consultancy
• Bioinformatics Solutions
  • Our Approach
  • Solutions
  • People and Experience
  • Tools and Innovation
• Genomic services
  • Gene Expression and SNP analysis
  • qPCR and cell line modelling
  • Bioinformatics
• Proprietary Discovery Arrays
  • Unique Content
  • Work with FFPE and fresh frozen tissue
  • Discover Targets, signatures and answers
• Resources
  • Technical Documentation
  • Posters and presentations
  • Publications

People and Experience

We employ a large and experienced PhD level bioinformatics and biostatistics team in 3 global locations. Our people are educated in a wide range of disciplines, including biology, medicine, mathematics and biostatistics.

Our team has extensive experience in designing studies and analysing complex data sets in pharmaceutical, biotech and diagnostic development settings.

We have unique experience in assay platform migration and analysis of expression data dervived from FFPE material.

Our experience also includes:

• Experience with internal research and development and commercial projects involving 1000+ samples per study.
• Development of custom methods, study designs and applications to deal with the specific nuances of FFPE material focusing on diagnostic, prognostic and predictive application.
  

Our team has also been involved in working with the FDA on the recent microarray quality control (MAQC) consortium publication on [the capabilities and limitations of various data analysis methods in developing and validating microarray-based predictive models].

Click Here for the MAQC paper.